I/C Graft Chambers are specially designed to perform in concert with the Graft Delivery System from DePuy. The I/C Graft Chamber can be mixed with various bioactive materials to capture the necessary biological stimulants to accelerate bone healing:
- I/C Graft Chamber Mixed with Autogenous Whole Blood: Whole blood can be added to the I/C Graft Chamber in combination with an activating agent to produce a fibrin clot that will improve the handling properties of the graft.
- I/C Graft Chamber Mixed with Autogenous Platelet Rich Plasma (PRP): PRP can be used as an osteopromotive carrier with the I/C Graft Chambers. The addition of PRP when using the SYMPHONY™ Platelet Concentration System achieves a measurable increase in growth factor concentration1. In addition, Platelet Derived Growth Factor (PDGF) has been shown to enhance DBM activity2.
- I/C Graft Chamber with Autogenous Bone Marrow: Bone marrow can be used as an osteopromotive carrier with the I/C Graft Chambers. The addition of bone marrow allows the capture of native levels of osteoprogenitor cells from the patient and can lead to improved bone formation3,4.
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General Processing Guidelines:
- Processed using proprietary and patented PAD™ (Pulsatile Acid Wave Demineralization) technology designed to enhance the osteoinductivity performance of DBM and reduce variability in the end product.
- Processed using proprietary and patented Allowash® technology to reduce the risk of disease transmission.
- Contains 100% DBM and cancellous chips, no inert carrier.
- Available in three volumes to accommodate a variety of clinical indications.
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| Code |
Description |
Sizing |
| GDS005 |
I/C Graft Chamber |
5 cc |
| GDS010 |
I/C Graft Chamber |
10 cc |
| GDS015 |
I/C Graft Chamber |
15 cc |
References
1. Kevy S, Jacobson M, et al. Characteristics of Platelet Concentrates Produced by Symphony™ PCS. 4th Annual Orthopedic Tissue Engineering Conference, New York, April 2000.
2. Howes R, Reddi A H, et al. Platelet-Derived Growth Factor Enhances Demineralized Bone Matrix-Induced Cartilage and Bone Formation. Calcified Tissue International, 1988, 42:34-38.
3. J F Connolly et al. Development of an Osteogenic Bone-Marrow Preparation. JBJS, 71:684-91; June 1989.
4. S P Bruder et al. Mesenchymal Stem Cells in Osteobiology and Applied Bone Regeneration. CORR, 344 Suppl: S247-56; October 1998.
