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Cellect DBM™ is an allograft mix designed to provide an appropriate environment for cell and bony in-growth.

The Cellect DBM™ Chambers are specially designed to perform in concert with the Cellect Graft Preparation Device from DePuy. The Cellect DBMTM Chambers are designed for the retention of osteoprogenitor cells.

  • Cellect DBM™ Chamber plus Autogenous Bone Marrow: Cellect DBM™ Chambers mixed with bone marrow obtained from bone marrow aspirate result in a graft matrix enriched with a 3-4 fold increase in osteoprogenitor cells4.
    • Increases the proportion of osteoprogenitor cells.
    • Reduces the proportion of other nucleated cells.
  • More cells. Proven Performance: Key published studies have reviewed the impact of increased cell concentration on bone formation. They have shown an improved healing response and bone formation1,2,3,4.

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General Processing Guidelines:

  • Processed using proprietary and patented PAD™ (Pulsatile Acid Wave Demineralization) technology designed to enhance the osteoinductivity performance of DBM and reduce variability in the end product.
  • Processed using proprietary and patented Allowash® technology to reduce the risk of disease transmission.
  • Contains 100% DBM and cancellous chips, no inert carrier.
  • Proprietary ratio of DBM fibers to cancellous chips designed for optimal cell attachment.

Code Description Sizing
CEL25 Cellect DBM™ 25 cc






References
1. J F Connolly et al. Development of an Osteogenic Bone-Marrow Preparation. JBJS, 71:684-91; June 1989.
2. S P Bruder et al. Mesenchymal Stem Cells in Osteobiology and Applied Bone Regeneration. CORR, 344 Suppl: S247-56; October 1998.
3. G F Muschler et al. Spine Fusion Using Cell Matrix Composites Enriched in Bone Marrow-Derived Cells. CORR, 407: 102-118, 2003.
4. S Kadiyala et al. Rapid Bone Regeneration in Femoral Defects by an Autologous Osteoprogenitor Cell Concentrate Prepared Using an Intraoperative Selective Cell Retention Technique. Transactions of the 49th Annual Meeting of the Orthopaedic Research Society, 2003.

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